Brain & Mind Preclinical research
Brain organoids preserved molecular signatures of their age for years
Long-lived human organoids followed reproducible developmental timing, offering a model—not a complete miniature brain.
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Brain & Mind
Neuroscience, cognition, memory, sleep, mental health and brain aging, clearly separated by research subject and study design.
7studies analyzed
6published in 2026
5human studies
1randomized studies
Research hubs
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These hubs combine the newest records with method guidance and live counts from the database.
Brain & Mind
Memory & Cognition Research
Human and animal studies of learning, working memory, planning and attention, labeled clearly by method and research subject.
Open research hub →Brain & MindBrain Aging Research
Alzheimer biomarkers, neuroinflammation, cellular aging and longitudinal brain change without turning risk markers into diagnoses.
Open research hub →Evidence mix
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Cell / organoid2Human5
Current and foundational research
Open database →7 complete evidence reviews
Brain & Mind Preliminary evidence
A cerebrospinal-fluid signal points to a possible route for schizophrenia cognitive symptoms
Northwestern researchers paired patient samples with a mouse model to identify a biomarker and test a drug candidate for cognitive impairment.
Brain & Mind Moderate evidence
Bone-marrow immune cells were found crossing into the aging human brain
NIH-highlighted research identified peripheral immune cells inside aging brain tissue, suggesting the blood-brain barrier becomes more permissive over time.
Brain & Mind Preliminary evidence
Brain immune activity may undergo a major shift in midlife
An NIH release describes postmortem hippocampal evidence from 40 healthy adults showing age-linked changes in immune-cell states.
Brain & Mind Preclinical research
Printed neurons communicated with living mouse brain slices
A Northwestern platform placed laboratory-grown neurons in defined patterns and recorded functional connections with ex vivo brain tissue.
Brain & Mind Preliminary evidence
Common immune cells produced a protein linked to schizophrenia risk
Stanford researchers found that neutrophils can produce C4A, adding a peripheral-immune source to a protein already implicated in brain development and schizophrenia.
Brain & Mind Moderate evidence
Exercise reduced depression symptoms across many trials, but certainty varied
Walking or jogging, yoga, and strength training produced meaningful average effects. The evidence was broad, but study quality and blinding remained serious limitations.